Professor Tham said all the work has been done in "laboratory settings".
"What the antibody treatment is designed to do is to actually have antibodies that target the spike protein. Because the spike protein is what the virus uses to enter cells. And so what the virus does is it has a lock and key mechanism between the spike protein and human cells. So, if you can actually bind an antibody that blocks spike from doing the interaction with the human cells, you stop virus infection.
"And so what we are trying to do is to unmask that scientific evidence that we know very well about the virus now and to actually develop two potent combinations of antibodies that gum up the function of spike, stop it from entering cells in laboratory settings, which we have identified, and by combining two different types of antibodies with which you can also stop the escape of mutations.
"What you're developing really are antibodies you can deliver to patients, that you know are already going to be safe, that are going to be potent, they're going to stop virus entry, stop virus infection, and they probably hopefully will work against all the variants that you have in the community.
"Antibody-based therapies can be used as prevention and treatment. So, what we're hoping to do is to provide it prior to
someone who has an infection. So, in particular, in settings of elderly populations, who can't mount an immune response, prior to outbreak you can deliver an antibody-based therapy to protect that population that wouldn't be able to amount an immune response."
Prof Tham said she couldn't give a timeline on when this treatment might be available though.
https://news.google.com/__i/rss/rd/articles/CBMib2h0dHBzOi8vd3d3LmFiYy5uZXQuYXUvbmV3cy8yMDIwLTA4LTI2L2Nvcm9uYXZpcnVzLWxpdmUtbmV3cy12aWN0b3JpYW4tcHJlbWllci1kYW5pZWwtYW5kcmV3cy1jb3ZpZC0xOS8xMjU5NDc1NNIBJ2h0dHBzOi8vYW1wLmFiYy5uZXQuYXUvYXJ0aWNsZS8xMjU5NDc1NA?oc=5
2020-08-26 00:35:00Z
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